Salivary Lactate Dehydrogenase Enzyme Activity in Oral Submucous Fibrosis: A Biochemical and Clinicopathological Study

Most adults and young alike are subject to anxiety and pressure and unfortunately, they react to this stress by becoming enslaved to regretful habits like paan, betel chewing with or without tobacco, smoking and alcoholism. These habits, though believed to alleviate tension to some extent, inevitably produce detrimental and addictive effects on the bodyespecially the oral cavity [1,2]. The fact that oral precancers or cancers is still a major health problem in the Indian sub-continent is largely due to the chewing of the betel quid or pan masala or the frequent use of tobacco smoking and / or chewing with or without betel quid (product of chewing betel leaf with areca nut and lime) [1,2]. Thus the early diagnosis and treatment of precancers is vital. A thorough knowledge of these lesions is essential at this early stage as it offers the best prognosis and the most effective approach to reduce morbidity and mortality for oral cancers.